Slay the Spire 2 Guides
Learn the fundamentals of Slay the Spire 2 with our in-depth guides, and stay up to date with the latest strategies as the game evolves in Early Access.
Beginner's Guide
Stop dying and start climbing
Core fundamentals for new players climbing the Spire
All Guides
Co-Op Multiplayer
See the differences from single-player mode
Team up with up to 4 players and conquer the Spire together
Ancients
Discover the mysterious blessings
Powerful NPC patrons who offer blessings at the start of each Act
Afflictions
Prepare for the dangerous debuffs
Negative card modifiers that enemies apply to your deck during combat
Enchantments
Uncover new ways to improve your cards
Positive card modifiers that unlock powerful synergies for your entire run
New in Slay the Spire 2
Ancients
Replace Boss Relics with powerful blessings offered by mysterious NPC patrons at the start of each Act.
Afflictions
Enemies can now debuff your cards directly — temporarily changing their cost or effect mid-combat.
Enchantments
Apply permanent positive modifiers to your cards, unlocking powerful synergies that last the entire run.