Unofficial Wiki & Strategy Guide
Slay the Spire 2
Your complete reference for every card, relic, potion, character, and mechanic. Built for players who want to climb higher.
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Game Database
Strategy Guides
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BeginnerBeginner's Guide
Stop dying and start climbing
Core fundamentals for new players climbing the Spire
Updated Mar 19, 2026
IntermediateCo-Op Multiplayer
See the differences from single-player mode
Team up with up to 4 players and conquer the Spire together
Updated Mar 19, 2026
IntermediateAncients
Discover the mysterious blessings
Powerful NPC patrons who offer blessings at the start of each Act
Updated Mar 17, 2026
What's New in Slay the Spire 2
Major systems introduced in STS2 that change how you build and play.
Co-Op Multiplayer
NewTeam up with up to 4 players. Share potions, coordinate debuffs, and use Mend at rest sites to heal allies.
Ancients
NewMysterious NPC patrons replace Boss Relics. Choose powerful blessings at the start of each Act.
Afflictions
NewEnemies can now debuff your cards directly — temporarily changing their cost or effect mid-combat.
Enchantments
NewApply permanent positive modifiers to your cards, unlocking powerful synergies for the entire run.
